The centre has contributions significant in elucidating the mechanisms by which pesticides, heavy metals, monomers, plasticizers and other plastic additives, solvents, food colours and dye intermediates act and elicit deleterious effects on human health.

Method for early diagnosis of manganese poisoning; a peripheral model for monitoring the neurological disorders caused by neurotoxic substances and test kits for the detection of toxic food adulterants have been developed.

Ability of some chelating agents in abrogating the toxicity due to metals and immunomodulators in case of solvents and monomers in animal models have been demonstrated. Vitamin B complex supplementation has been found to diminish susceptibility to lead and cadmium intoxication.

The centre has contributed significantly to Drinking Water Mission, Ganga Action Plan, Technology Mission on Edible Oils and Pulses, Global Climatic Change programme and All India co-ordinated programmes on food colours, pesticides and metal exposure assessment.

Microorganisms have been isolated which have the potential of degrading pesticides such as DDT, Endosulfan and lindane in the sites contaminated with them.

The institute has undertaken the challenging assignment on testing of newer products reaching the markets including bio-engineered products.